| Datum | Tijd | Thuis | Uit |
|---|
| 24-10-2021 | 17:00 | Zorg en Zekerheid Leiden M22 1 | BC APOLLO Amsterdam M22 1 |
| 27-10-2021 | 19:30 | BC APOLLO Amsterdam M22 1 | Amstel State M22 1 |
| 31-10-2021 | 16:00 | BC APOLLO Amsterdam M22 1 | UBALL M22 1 |
| 20-11-2021 | 20:30 | D.B.V. Rowic M22 1 | BC APOLLO Amsterdam M22 1 |
| 26-11-2021 | 21:00 | Rotterdam Basketbal M22 1 | BC APOLLO Amsterdam M22 1 |
| 27-11-2021 | 20:00 | BC APOLLO Amsterdam M22 1 | TBG Dragons M22 1 |
| 04-12-2021 | 20:00 | BC APOLLO Amsterdam M22 1 | Almere Pioneers M22 1 |
| 12-12-2021 | 17:00 | Landstede Hammers M22 1 | BC APOLLO Amsterdam M22 1 |
| 17-12-2021 | 20:00 | Basketbal Academie Limburg M22 1 | BC APOLLO Amsterdam M22 1 |
| 14-01-2022 | 20:45 | Amstel State M22 1 | BC APOLLO Amsterdam M22 1 |
| 23-01-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | CTO M22 1 |
| 29-01-2022 | 14:30 | Heroes Den Bosch M22 1 | BC APOLLO Amsterdam M22 1 |
| 06-02-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | BC Triple Threat M22 1 |
| 13-02-2022 | 15:00 | Donar Groningen M22 1 | BC APOLLO Amsterdam M22 1 |
| 20-02-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | Zorg en Zekerheid Leiden M22 1 |
| 26-02-2022 | 19:00 | UBALL M22 1 | BC APOLLO Amsterdam M22 1 |
| 06-03-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | Rotterdam Basketbal M22 1 |
| 12-03-2022 | 13:30 | TBG Dragons M22 1 | BC APOLLO Amsterdam M22 1 |
| 20-03-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | D.B.V. Rowic M22 1 |
| 26-03-2022 | 08:30 | Almere Pioneers M22 1 | BC APOLLO Amsterdam M22 1 |
| 03-04-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | Landstede Hammers M22 1 |
| 10-04-2022 | 16:00 | BC APOLLO Amsterdam M22 1 | Basketbal Academie Limburg M22 1 |
